Category Archives: conflicts of interest

A review of two new books that attack the DSM-5, psychiatry’s “bible”

Share I reviewed two books now circulating about the DSM and the current controversy over the DSM-5 for The American Scholar — see review here. The two books are The Book of Woe: The DSM and the Unmaking of Psychiatry by … Continue reading

Posted in antidepressants, antipsychotic drugs, conflicts of interest, drug marketing, FDA, pharmaceutical industry, prescription drug abuse, scientific misconduct | Tagged , , , , , , , , | Leave a comment

Martin Keller, principal investigator of Paxil study 329, retires from Brown University

Share I just learned that Dr. Martin Keller, principal investigator of the controversial Paxil study 329, has retired from his position as a professor of psychiatry at Brown University — see here. As Pharmalot notes, Keller quietly retired June 30 in … Continue reading

Posted in antidepressants, clinical trials, conflicts of interest, drug marketing, ghostwriting, pharmaceutical industry, scientific journal retractions, scientific misconduct | Tagged , , , , , | 2 Comments

Calls for action against authors of controversial Paxil study are getting louder

Share In the wake of GlaxoSmithKline’s record-breaking $3 billion settlement with the U.S. Department of Justice, a number of psychiatrists and researchers have redoubled their efforts to get Paxil study 329 retracted. As mentioned here and in other news accounts, the … Continue reading

Posted in antidepressants, clinical trials, conflicts of interest, drug marketing, ghostwriting, National Institutes of Health, pharmaceutical industry, scientific journal retractions, scientific misconduct, university industry collaboration | Tagged , , , , , , , | 2 Comments

US Senator raises concerns about possible stock manipulation by Vertex executives

Share Senator Charles Grassley is upping the ante on the controversy surrounding the Vertex pharmaceutical executives who cashed in on overstated clinical trial data — see my blog from last week. According to The Boston Globe, which broke the Vertex … Continue reading

Posted in biotech industry, clinical trials, conflicts of interest, pharmaceutical industry, Uncategorized | Tagged , , , , , , | 1 Comment

Vertex pharmaceutical executives cash in on false hopes

Share Senior executives at Vertex Pharmaceuticals made millions of dollars each by selling company stock in the days after the Cambridge-based pharmaceutical reported promising clinical trial data on an experimental drug for cystic fibrosis. And then weeks after they cashed … Continue reading

Posted in biotech industry, clinical trials, conflicts of interest, drug marketing, pharmaceutical industry, Uncategorized | Tagged , , , , , | 4 Comments

Fast-moving bill in Congress would weaken FDA oversight of new drugs and devices

Share Congress is moving quickly to pass a bill that would authorize higher industry fees for the FDA in exchange for speeding up the approval of some drugs and medical devices and eliminating restrictions on financial conflicts of interest among … Continue reading

Posted in clinical trials, conflicts of interest, drug marketing, FDA, medical devices, pharmaceutical industry, public health | Tagged , , , , , | 1 Comment

Why 60 Minutes suddenly discovered the placebo effect in treating depression

Share When Dr. Irving Kirsch published his meta-analysis in PLoS Medicine in February 2008 showing that antidepressants were no more effective than a placebo in treating mild or moderate depression, the national news media ignored his explosive findings, for the … Continue reading

Posted in antidepressants, conflicts of interest, drug marketing, health care costs, pharmaceutical industry | Tagged , , , , | 16 Comments

When it comes to scientific misconduct, should there be a statute of limitations?

Share I was hesitant to weigh in at first when I learned that Brown University’s School of Medicine had decided not to pressure a psychiatric journal to retract the seriously flawed Paxil study that I wrote about in Side Effects. … Continue reading

Posted in antidepressants, clinical trials, conflicts of interest, FDA, ghostwriting, pharmaceutical industry, scientific journal retractions, scientific misconduct | 7 Comments

Enforcing anti-kickback laws: a powerful deterrent against ghost-writing in medicine

Share The Obama administration recently made it clear that it will require drug companies to disclose the payments they make to doctors for research, consulting, speaking, travel and entertainment under the new health care law — see the New York … Continue reading

Posted in antidepressants, conflicts of interest, continuing medical education, drug marketing, ghostwriting, pharmaceutical industry, university industry collaboration | Tagged , , , , , | Leave a comment

From the Pentagon Papers to Allen Jones: Why it’s so hard to be a whistleblower

Share Allen Jones, the whistleblower in an ongoing landmark trial against the pharmaceutical giant Johnson & Johnson, was very much on my mind this past weekend. I was participating in a workshop to develop curriculum to teach college students about … Continue reading

Posted in antipsychotic drugs, conflicts of interest, drug marketing, expert testimony, media coverage, pharmaceutical industry, whistleblowing | Tagged , , , , , , , | 5 Comments